Nifedipine Rectal Ointment for Anal Fissures and Hemorrhoids in Winnipeg
Are you suffering from the pain, itch and irritation of anal fissures or hemorrhoids?
Are you looking for compounded nifedipine rectal ointment?
Our compounding pharmacy makes nifedipine rectal ointment.
Nifedipine ointment has been shown to be very effective in the treatment of anal fissures and hemorrhoids. It is very well tolerated with minimal potential side effects.
Please note that we are a Canadian pharmacy operating in Winnipeg, Manitoba and we are unable to ship nifedipine ointment to the United States. If you are an American citizen please see the bottom of this page for information on how to find a compounding pharmacy near you.
For more detailed information about,
- how nifedipine rectal ointment works
- the potential areas of concern with its use
- other resources
- and how to find it where you live
…scroll down and keep reading below.
You can get single-ingredient, nifedipine 0.2% ointment at Tache Pharmacy TODAY! We always have it in stock.
We also make combination ointments and rectal rocket suppositories.
These compounded products are for the treatment of anal fissures.
Visit our contact us page for more contact information.
Feel free to download and print our anal fissures prescription template. You can provide this to your physician.
Do you already have a prescription for nifedipine rectal ointment?
Use our online prescription order form to submit your prescription to us.
What is nifedipine ointment?
Nifedipine ointment is a medicated ointment containing 0.2% nifedipine.
Other strengths of this anal fissure ointment can be made but 0.2% is the most common strength.
Other ingredients, such as lidocaine for pain, can also be added.
A study by Farzaneh Golfam, Parisa Golfam, Alireza Khalaj, Mortaz Sayed Saaid Sayed titled “The effect of topical nifedipine in treatment of chronic anal fissure” found the following:
“Patients in the nifedipine group showed significant healing and relief from pain compared with patients in the control group.
Recurrence rate with nifedipine use in spite of control of predisposing factors such as constipation was significant.
Another finding was low complication rate with this treatment.”
Essentially this study found that nifedipine ointment is very effective in treating anal fissures while being very well tolerated.
What are anal fissures?
Anal fissures are small tears in the skin that lines the anus.
These tears typically extends into a circular ring of muscle called the internal anal sphincter.
Once a fissure develops, the internal anal sphincter typically goes into spasm.
This spasming causes:
- further separation of the tear
- impairs healing
- and causes pain.
Exposure to feces can slow healing. The stools can cause a tearing, ripping and/or burning sensation after each bowel movement. Rectal pain can last several minutes to hours.
It is estimated that 1 out of 5 people (20%) will develop an anal fissure during their lifetime.
Approximately 80 to 90% of patients heal with a topical treatment such as nifedipine ointment.
How does nifedipine ointment work for treating anal fissures?
Chronic anal fissures are known to be linked with a continuous, excessive muscle tone (flexing) and spasm of the internal anal sphincter.
Nifedipine ointment works by helping to relax the smooth muscle around the anus. This reduces the internal anal sphincter pressure which decreases pain.
The medication also dilates the blood vessels. This promotes better blood flow to the injured area. The increase in blood flow helps heal the fissure.
Essentialy, every treatment method for anal fissures aims to reduce internal anal sphincter pressure and decrease the anal sphincter spasm associated with chronic anal fissures.
These are the main mechanism of action of nifedipine ointment. It also has the added benefit of increasing blood flow to the area.
How do I use this ointment?
Apply a small, pea-sized amount with your finger.
Ointment should be applied just outside the anal canal (preferably not directly to the fissure which could cause discomfort).
The medication should be applied two to three times a day.
However, you should follow the directions given by your physician on the prescription label if different.
Wash your hands before and after each application.
You may also wish to wear a glove or use a finger cot.
You should also apply this ointment after each bowel movement.
It can take several weeks for the fissure to heal.
Be sure to use the medication for the entire treatment period.
Download our Anal Fissures Patient Information Sheet.
What side effects can occur with nifedipine rectal ointment?
Side effects are very uncommon with this medication.
Side effects usually occur at the start of therapy. This is due to the fact that the skin is damaged and the medication may be absorded into the bloodstream.
These side effects include:
- Perianal itching or soreness
Rare side effects, that you should report right away to your prescriber or pharmacist, include:
- Fast or irregular heart rate
- Vision Changes
- Swollen or tender gums
- Dizziness or weakness
What other anal fissure management regimens / treatments should I use?
Typically you want to start a bowel regimen that includes:
- a stool softener (e.g. docusate)
- 25-35 grams of fiber daily
- adequate hydration
- sitz baths for comfort.
What other ingredients are used for topical treatment of anal fissures?
The main ingredients used in the treatment of anal fissures are:
Nifedipine and diltiazem are never combined together but can be found in anal fissure topical ointment in the following concentrations:
- Nifedipine 0.2%
- Nifedipine 0.3%
- Nifedipine 0.5%
- Diltiazem 2%
If necessary, nifedipine or diltiazem can be mixed with:
- Lidocaine 1%
- Lidocaine 2%
- Hydrocortisone 1%
- Hydrocortisone 2%
- Sucralfate 2%
- Sucralfate 4%
- Sucralfate 7%
- Misoprostol 0.0024%
For physicians, visit our physician portal page for a prescription template called Rectal Fissure Fact Sheet.
We try to always have nifedipine 0.2% ointment in stock in 30 gram tubes.
Patients can usually pick up nifedipine 0.2% ointment the same day.
Other strengths and combinations can take a day or two for our compounding pharmacy to make.
To learn more about anal fissures and their treatment visit https://www.uptodate.com/contents/anal-fissure-beyond-the-basics
How To Find Nifedipine Anal Fissure Ointment At A Pharmacy Near You
If you do not live in Canada or you are in Canada but don’t live near Winnipeg you can still find nifedipine ointment near you.
Simply use the following search terms in Google exactly as typed here. We suggest copying and pasting these search terms into Google search.
“compounding pharmacy near me” + “nifedipine ointment”
If that doesn’t work to show a pharmacy that specifically makes nifedipine ointment simply search “compounding pharmacy near me” and then give them a call. If you ask them if they make nifedipine ointment there is a good chance that they can.
You can also reach out to PCCA at a www.pccarx.com to find a compounding pharmacy near you.
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