Caring for you just like we would want to be cared for.

Magic Mouthwash

Magic Mouthwash in Winnipeg

Are you looking to have your Magic mouthwash made by a compounding pharmacy in Winnipeg? 

Tache Pharmacy has a compounding pharmacy lab that regularly compounds mouthwashes and rinses.

To learn more about having your mouthwash compounded by Tache Pharmacy call us at (204) 233-3469 , email us at or visit our contact us page for more contact information.

Do you have a prescription for magic mouthwash?  Feel free to use our online prescription order form to submit your prescription to us.

Order Your Magic Mouthwash Now!

Please note that we are a Canadian pharmacy operating in Winnipeg, Manitoba and we are unable to ship magic mouthwash to the United States.

What are Compounded Prescription Mouthwashes Used For?

Prescription mouthwashes are used to treat mouth sores also known as oral mucositis.  These mouth sores are usually caused by cancer chemotherapy and/or radiation therapy.  There may be other causes or reasons for using a compounded prescription mouthwash.  For example, oral surgeries and thrush.

Since these mouth sores can be very painful and disrupt eating and drinking it is important to treat the mouth sores.  Prescription mouthwashes can relieve the pain caused by oral mucositis.

These mouth rinses may also be used to treat damage or sores in the throat and esophagus as well.  In these cases the mouthwash may also be swallowed.

If a mouthwash is to be swallowed, special consideration needs to be given to the active ingredients in the preparation.  Our pharmacists have specialized knowledge and experience with regards to the ingredients that can be used.

Magic Mouthwash Formulas / Recipes

The active ingredients in the recipes for compounded prescription mouthwashes can vary depending on the degree of ulceration and redness in the tissues of the mouth and the other symptoms needing to be treated.  Your doctor, along with our compounding pharmacists, will help determine the best combination of ingredients for you.

Feel free to download and print our mouthwash prescription template and share it with your doctor.

Download Our Mouthwash Prescription Template!

Although the specific combination of ingredients may vary, these products often include a mixture of:

  • antihistamines (diphenhydramine, chlorpheniramine)
    • creates an anesthetic or pain relieving effect
  • corticosteroids (hydrocortisone, dexamethasone, clobetasol)
    • reduces inflammation and aids in healing
  • antibiotics (tetracycline)
    • to stop bacterial infections
  • antifungal medications (nystatin, clotrimazole)
    • to stop fungal infections
  • anti-inflammatory agents
    • to reduce inflammation
  • topical anesthetics (tetracaine, lidocaine)
    • to reduce pain and irritation
  • liquid antacid
    • to help the medication coat the tissues of the mouth

Other common ingredients include:

  • misoprostol
    • anti-inflammatory and protective properties for mouth mucosa
  • gabapentin
    • reduces pain and burning in the mouth
  • sucralfate
    • provides a protective coating as it tends to bind to the unprotected proteins of injured mucosal cells
    • may promote the local generation of prostaglandin E2 which leads to elevated blood flow, production of mucous, increased cell division, and the migration of cells.  All important steps in the healing process.
    • binds with growth factors and effects the growth and formation of new blood vessels therefore it boosts mucosal healing
  • ketamine (requires a triplicate prescription)
    • pain relief
  • morphine (requires a triplicate prescription)
    • pain relief

The most common Magic Mouthwash formula contains diphenhydramine 0.075%, hydrocortisone 0.125%, nystatin 7500u/ml and lidocaine 0.4%.

Another common mouthwash recipe is called Super Magic Mouthwash and contains diphenhydramine 0.125%, dexamethasone 0.00033%, tetracycline 1.25% and lidocaine 1%.

Pink Lady contains Xylocaine Viscous 2% mixed with Maalox in a 1:1 ratio.

Modified Pink Lady is a mix of Xylocaine Viscous 2%, Maalox and Benadryl Elixir in a 1:1:1 ratio.

A study titled “Survey of topical oral solutions for the treatment of chemo-induced oral mucositis” by Alexandre Chan and Robert J Ignoffo (Journal of Oncology Pharmacy Practice 11 (4), 139-143, 2005) found the following:

“Forty institutions returned surveys during the study period.

The top five ingredients used to compound the magic mouthwash are diphenhydramine (Benadryl), viscous lidocaine, magnesium hydroxide/aluminum hydroxide, nystatin and corticosteroids.

Most institutions administer the mouthwash every 4 hours (36%) or every 6 hours (36%).”

These mouthwashes are commonly used by patients of CancerCare Manitoba.

Physicians, if you are looking for a list of common mouthwash formulas please visit our Physician Portal page and view the Mouthrinse Formulas document.

Magic Mouthwash Instructions

Note: Always follow your specific directions as prescribed by your doctor.

Depending on the type of mouthwash / mouthrinse you have been prescribed, your specific instructions will vary.

Generally, these mouthwashes are either swished and then spit out or they are swished and then swallowed (swallowing is more common if there are issues with the esophagus).  Do NOT swallow the mouthwash unless instructed by your doctor.

Most commonly 5 to 10mL (or 5 to 15mL) are swished for 1 to 2 minutes two to four times a day.  The frequency may be at shorter intervals depending on the needs of the patient.  Also, we do see volumes up to 30mL used per dose if required.

Measuring syringes will be provided by Tache Pharmacy to aid in the measurement of your dose.

Download our Magic Mouthwash Patient Information Sheet.

Additional Information

For more information on Oral Mucositis and Compounded Mouthwashes click on the link.  Patients, to learn more on nonpharmacological treatments, visit the Treatment section of the article.

Order Your Magic Mouthwash Now!


The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes only. The purpose of this website is to promote broad consumer understanding and knowledge of various health topics. It is not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.